| HIV/AIDS
Medical Research |
| Program |
Institution |
Amount*
(U.S. Dollars) |
OPERATIONAL RESEARCH INVOLVING ARV |
| Assessment
of affordable and effective anti-retroviral regimens for HIV-infected
children in developing countries |
University
of Natal, Oxford Hospital (Human Immunology Unit), Baylor College
of Medicine, Ottawa Hospital, Amsterdam Medical Centre |
370,000 |
| The
Adult Antiretroviral Treatment and Resistance Study (The Tshepo
Study) |
Dr.
Richard Marlink, Botswana-Harvard Partnership, and Botswana
Ministry of Health, Harvard AIDS Institute, Princess Marina
Hospital and McGill AIDS Centre, McGill University |
17,100,000 |
| The
BANA Study. A pilot trial in Gaborone, Botswana of long-term
therapy with Stavudine (d4T) plus Didanosine (ddI) versus Stavudine
plus Didanosine plus Hydroxyurea (HU) in HIV-infected infants
and children |
Princess
Marina Hospital, Baylor College of Medicine |
3,800,000 |
| An
evaluation of CD4+ and CD8+T cell apoptosis as surrogate markers
for monitoring progression of disease in HIV-1 infected children
– a single centre study |
University
of Stellenbosch |
111,000 |
| Induction
and augmentation of protective immune responses to achieve effective
and durable control of HIV in adult and paediatric infection
in sub-Saharan Africa |
University
of Natal, Harvard Medical Schooln |
790,000 |
TRIALS IN OPPORTUNISTIC
INFECTIONS |
| An
investigation into the relationship between HIV-1, Injectable
Progestogen Contraceptives, Cervical cancer and Sexually Transmitted
Infections |
University
of Cape Town, Sloane Epidemiology Unity, Boston University |
227,354 |
| Burden
of disease caused by respiratory viruses and Pneumocystis
carinii pneumonia in African HIV –infected children
hospitalised for acute lower respiratory tract infections |
University
of Witwatersrand |
95,000 |
| Establishing
the prevalence of viral Hepatitis B and C infection newly diagnosed
HIV infected patients so as to support the routine screening
of these tests in these patients |
University
of Witwatersrand |
141,492 |
| Prophylactic
intrapartum antibiotics for delivery in HIV positive women |
University
of Natal (Nelson Mandela School of Medicine) and University
of Transkei |
271,000 |
| The
Cost- Effectiveness of HIV/AIDS treatment in the Western Cape,
South Africa |
Prof
R Wood; Dr JG Kahn; Mr B Haile & Consultants |
34,000 |
| The
Cost- Effectiveness of HIV/AIDS treatment in the Western Cape,
South Africa |
Somerset
Hospital, University of Cape Town |
106,535 |
TRIALS OF SELF-CARE, NUTRITION AND OTHER NON ARV THERAPIES |
| Phase
1-Fortification trials of Sorghum flour in Botswana Phase 2-The
effect of Fortified Sorghum Meal of Weight Changes and nutritional
related side effects of HIV Positive Adults in Botswana |
National
Food Technology research Centre |
347,420 |
| Self-care
symptom management for persons with HIV disease |
International
Network of Nurse Scientists, University of California |
426,080 |
| The
use of Zioc and a trace element mixture plus multivitamin supplement
to reduce morbidity in HIV-infected children in Cape Town |
Child
Health Unit, Department of Paediatrics, University of Cape Town |
295,000 |
TRIALS IN MTCT |
| A
randomised control study to assess the role of post-exposure
prophylaxis in reducing mother to child transmission of HIV-1
in infants born to mothers without access to anti-retroviral
therapy |
University
of Witwatersrand, Perinatal HIV Research Unit |
42,000 |
| HIV
drug resistance in pregnant women and their infants: Effects
of short-course anti-retroviral treatment to prevent perinatal
transmission |
AIDS
Unit National institute for Virology, Perinatal HIV Research
Unit Chris Hani Baragwanath Hospital, South African Institute
for Medical Research |
98,932 |
| HIV
drug resistance in pregnant women and their infants: Effects
of short-course anti-retroviral treatment to prevent perinatal
transmission |
Chris
Hani Baragwanath Hospital, AIDS Unit National institute for
Virology, University of Witwatersrand and University of Cape
Town |
32,000 |
TRIALS IN TB |
| A
pilot for the development, implementation and evaluation of
enhanced informed consent documentation and processes for smear
negative TB in HIV+ve adults trial in a developing country |
Medical
Research Council - Burden of Disease Research Unit |
25,741 |
| Deriving
an accurate and cost-effective approach to the diagnosis of
smear-negative tuberculosis in HIV-infected adults in a developing
country |
University
of Cape Town (Infectious Disease Research Unit) |
171,000 |
| Evaluation
of the efficacy off isoniazid prophylaxis in preventing tuberculosis
and the effectiveness of cotrimoxazole in reducing the burden
of Pneumocystis carinii pneumonia in African children |
University
of Witwatersrand |
1,158,511 |
| Novel
Diagnostic tests for the diagnosis and monitoring of childhood
and adult TB |
University
of Cape Town, Department of Paediatrics Imperial College, London |
590,377 |
| Randomised
clinical trial to evaluate the optimal duration of tuberculosis
chemotherapy in human immunodeficiency virus infected children
with tuberculosis and to assess the effect of tuberculosis on
the natural history of human immunodeficiency virus infection |
University
of Stellenbosch, University of Cape Town, Medical University
of South Africa, Windhoek Central Hospital (Namibia), Brewelskloof
Hospital (Worcester) |
1,473,000 |
TRAINING / EDUCATION |
| Bi-directional
Physician Exchange Program |
Baylor
College of Medicine |
$
2,560,966 |
| Centre
for Excellence in Botswana |
Princess
Marina Hospital, Baylor College of Medicine , Texas Children's
Hospital |
6,000,000 |
| Establishing
an information portal as an integrated system incorporating
global health information initiatives relating to HIV/AIDS for
the benefit of SADC countries, with a view to be rolled out
into other African states |
Medical
Research Council |
357,000 |
| Expansion
and implementation plan for the fourteen South African Development
Community Nations |
Baylor
College for Medicine |
310,000 |
| How
to Counsel on Infant Feeding Practices in Southern Africa in
a time of HIV/AIDS |
University
of Cape Town |
190,469 |
| Nursing
Education Program |
Baylor
College of Medicine and Nursing School in South Africa, SADC
Aids Network of Nurses and Midwives (SANNAM), USAIDS, National
Nursing Association |
325,000 |
| Oral
HIV/AIDS Education, Diagnosis and Training Programme for Oral
Health Personnel |
Dept.
of Community Dentistry, University of Stellenbosch |
355,000 |
| The
impact of an early diagnosis of HIV infection status in vertically
exposed infants in low resource setting |
Wits
Health Consortium, Coronation Women & Children's Hospital, Johannesburg
Hospital |
145,000 |
| The
impact of incorporating relevant health care options into education
and counselling programmes |
uMngeni
AIDS Centre; University of Natal; Communicable Diseases Clinic:
Grey's and Edendale Hospitals, Church of Ascension |
54,300 |
| Youth
AIDS Project |
University
of Cape Town, Aids project for kids |
26,000 |
LABORATORY STUDIES |
| CD4+
T cell enumeration: use of CD45, CD3, CD4 and SS parameter gating
without the necessity for a Lymphocyte differential |
Flow
Cytometry Unit, Department of Molecular Medicine and Haematology,
South African Institute for Medical Research and the School
of Pathology University of Witwatersrand. |
9,000 |
| Cell-associated
virus in breastmilk of HIV Seropositive women |
Department
of Paediatrics & Child Health, University of Natal and Ottawa
General Hospital Research Institute |
24,000 |
| Management
of abnormal cytology in HIV-1 infected women (MACH-1) |
Research
for the Future |
801,132 |
| Rapid
HIV saliva tests for the surveillance and clinical diagnosis
of HIV infection in South African children between 12 to 24
months of age |
University
of Witwatersrand |
8,301 |
| The
feasibility of performing rapid HIV testing in community pharmacies:
a pilot study in the Western Cape |
University
of the Western Cape |
2,507 |
| The
pharmokinetics and efficacy of oral compared with intravenous
trimethoprim-sulphamethoxazole (TMP-SMZ) for treatment of Pneumocystis
carnii (PCP) in HIV-infected children (Phase 2) |
University
of Cape Town |
31,000 |
| The
Pharmacokinetics of oral Cotrimaxazole in HIV-Infected Children:
Phase 1 |
University
of Cape Town |
6,000 |
PSYCHOSOCIAL STUDIES |
| Acceptability
study of Mother to child HIV transmission intervention programme
in Khayelitsha |
Yale
University, Dept Paediatrics (University of Cape Town), Dept
of Community Health (UCT), Dept of Obstetrics & Gynaecology
(UCT) |
5,000 |
| An
investigation into the nature and extent of the impact of AIDS
on orphans: A study of conditions for orphans in rural and urban
areas of Botswana and the implications for future poverty levels
in Botswana |
Government
of Botswana, Princess Marina Hospital |
17,000 |
| Male
involvement in mother to child (MTCT) HIV prevention in Botswana
– maximising support to the programme |
Botswana-Harvard
Partnership |
32,000 |
| Risk,
Resilience and the Psychosocial Adjustment of Adolescent AIDS
Orphans |
University
of Cape Town |
10,074 |
| The
study aims to increase partner compliance of STD patients |
Bethal
Hospital |
9,000 |
| Traditional
Healers in the Management of HIV/AIDS |
Department
of Community Health, School of Public Heath, Faculty of Health
Sciences, Wits |
11,179 |
| Rapid
AIDS Mortality in South Africa |
Medical
Research Council – Burden of Disease Research Unit, University
of Cape Town |
174,000 |
| The
impact of TB, HIV, STD, Hepatitis C and substance abuse in correctional
service institutions on women and children |
Dept
of Correctional Services; Medical University of South Africa
(MEDUNSA), US Consultants |
535,000 |
| |
|
*U.S. amounts
reported are subject to foreign currency fluctuations.
|
